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Article

DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism

25 Jan 2005

Abstract excerpt

The aim of this study was to investigate whether the DNA methylation pattern within the alpha synuclein promoter region is altered in intoxicated and early abstinence patients with alcoholism undergoing alcohol withdrawal. We observed a significant increase of the alpha synuclein promoter DNA methylation in patients with alcoholism which was significantly associated with their elevated homocysteine levels. No...

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PMID: 15671870
DOI: 10.1097/00001756-200502080-00020

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