Article
[Neurodegeneration and epigenetics].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology - 1 Nov 2012
Iwata Atsushi
Abstract excerpt
Alpha-synuclein (SNCA) gene expression is an important factor in the pathogenesis of Parkinson's disease (PD). Gene multiplication can cause inherited PD, and promoter polymorphisms that increase SNCA expression are associated with sporadic PD. CpG methylation in the promoter region may also infl...
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