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SNCA Gene Methylation in Parkinson’s Disease and Multiple System Atrophy

6 Feb 2023

Abstract excerpt

In recent years, epigenetic mechanisms have been implicated in the development of multifactorial diseases including neurodegenerative disorders. In Parkinson’s disease (PD), as a synucleinopathy, most studies focused on DNA methylation of SNCA gene coding alpha-synuclein but obtained results were rather contradictory. In another neurodegenerative synucleinopathy, multiple system atrophy (MSA), very few studies...

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PMID: 36810559
DOI: 10.3390/epigenomes7010005

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