Article

Multitissue Multiomics Integration Reveals Tissue-Specific Pathways, Gene Networks, and Drug Candidates for Type 1 Diabetes

2024-11-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Aims/hypothesis</h4> Although genome-wide association studies (GWAS) have identified loci associated with Type 1 diabetes (T1D), the specific pathways and regulatory networks linking these loci to disease pathology remain largely unknown. We hypothesized that T1D genetic risk factors disrupt tissue-specific biological pathways and gene networks that ultimately lead to beta cell loss. <h4>Me...

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Literature Corpus work: f6aea2bd-23b0-51ac-beae-984b16eb48ce
DOI: 10.1101/2024.11.25.24317912

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