Article

TRAJ23 Gene Targeting as a Therapeutic Strategy for Type 1 Diabetes: Implications from NOD Mouse Model Studies

2024-06-14

Abstract excerpt

<title>Abstract</title> <p>Type 1 Diabetes (T1D) is an autoimmune disease characterized by the attack and destruction of Pancreatic islet beta cells by T cells. Understanding the role of T-cell receptor (TCR) in the development of T1D is of paramount importance. This study employs single-cell RNA sequencing (scRNA-seq) to delve into the mechanistic actions and potential therapeutic applications of autoreactive st...

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Literature Corpus work: 57d6da99-43cc-5318-bfdf-ac9d898acb03
DOI: 10.21203/rs.3.rs-4425280/v1

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