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Article

Association testing in a linked region using large pedigrees.

American journal of human genetics - 1 Mar 2005

Cantor Rita M, Chen Gary K, Pajukanta Päivi, Lange Kenneth

Abstract excerpt

This report describes computer implementation of a scheme for joint linkage and association analysis. The model implemented in the computer package Mendel estimates both recombination and linkage-disequilibrium parameters and conducts likelihood-ratio tests for (1) linkage alone, (2) linkage and association simultaneously, and (3) association in the presence of linkage. Application of the method to data from...

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Identifiers

PMID: 15657872
DOI: 10.1086/428628
PMCID: PMC1196405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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