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Article

A sib-pair regression model of linkage disequilibrium for quantitative traits.

Human heredity - 1 Jan 2000

Cardon L R

Abstract excerpt

A multiple-regression model is described for the detection of linkage disequilibrium in quantitative trait loci. The model is developed for application to large numbers of single nucleotide polymorphism (SNP) markers genotyped on small nuclear families. Parental data are not required by the method, although it provides a direct means to test quantitative trait locus-marker allele association and to determine...

Topics

Humans
Linkage Disequilibrium
Models, Genetic
Multivariate Analysis
Nuclear Family
Polymorphism, Single Nucleotide
Quantitative Trait, Heritable

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10899753
DOI: 10.1159/000022940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10899753-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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