Article
Identification of linked regions using high-density SNP genotype data in linkage analysis.
Bioinformatics (Oxford, England) - 1 Jan 2008
Lin Guohui, Wang Zhanyong, Wang Lusheng, Lau Yu-Lung, Yang Wanling
Abstract excerpt
MOTIVATION: With the knowledge of large number of SNPs in human genome and the fast development in high-throughput genotyping technologies, identification of linked regions in linkage analysis through allele sharing status determination will play an ever important role, while consideration of recombination fractions becomes unnecessary. RESULTS: In this study, we have developed a rule-based program that...
Topics
- Chromosome Mapping
- DNA Mutational Analysis
- Databases, Genetic
- Genetic Markers
- Genetic Predisposition to Disease
- Genetic Testing
- Genotype
- Humans
- Linkage Disequilibrium