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Article

Haplotype structure of TNFRSF5-TNFSF5 (CD40-CD40L) and association analysis in systemic lupus erythematosus.

European journal of human genetics : EJHG - 1 May 2005

Chadha Sapna, Miller Katie, Farwell Lisa, Lightstone Liz B, Daly Mark J, Rioux John D, Vyse Timothy J

Abstract excerpt

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease that is caused by genetic and environmental factors. The tumour necrosis factor (TNF) superfamily of genes play a central role in immune regulation and have been proposed to be involved in the development of SLE. TNFRSF5 (CD40) falls on 20q11-13, a region linked with SLE in three independent genome-wide studies. TNFSF5 (CD40L) falls on Xq26 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15657613
DOI: 10.1038/sj.ejhg.5201367

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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