Article
A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene.
PloS one - 1 Jan 2014
Ciccacci Cinzia, Perricone Carlo, Ceccarelli Fulvia, Rufini Sara, Di Fusco Davide, Alessandri Cristiano, Spinelli Francesca Romana, Cipriano Enrica, Novelli Giuseppe, Valesini Guido, Borgiani Paola, Conti Fabrizio
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease with complex pathogenesis in which genes and environmental factors are involved. We aimed at analyzing previously identified loci associated with SLE or with other autoimmune and/or inflammatory disorders (STAT4, IL10, IL23R, IRAK1, PSORS1C1, HCP5, MIR146a, PTPN2, ERAP1, ATG16L1, IRGM) in a sample of Italian SLE patients in order to verify or...
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