Article
Haplotype analysis of tumour necrosis factor receptor genes in 1p36: no evidence for association with systemic lupus erythematosus.
European journal of human genetics : EJHG - 1 Jan 2006
Chadha Sapna, Miller Katie, Farwell Lisa, Sacks Steven, Daly Mark J, Rioux John D, Vyse Timothy J
Abstract excerpt
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with partially understood aetiology. The 1p36 region has been previously linked with SLE and harbours tumour necrosis factor receptor (TNFR) genes. Functional and genetic data implicate their gene products in SLE and other autoimmune diseases. In all, single-nucleotide polymorphisms (SNPs) across TNFRSF14 (HVEM), and 43 SNPs across the TNFRSF8...
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