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Article

Oral clefts, maternal smoking, and TGFA: a meta-analysis of gene-environment interaction.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jan 2005

Zeiger Joanna S, Beaty Terri H, Liang Kung-Yee

Abstract excerpt

OBJECTIVE: A meta-analysis was performed to examine the association among maternal cigarette smoking, infant genotype at the Taq1 site in the transforming growth factor alpha (TGFA) locus, and risk of nonsyndromic oral clefts, both cleft palate (CP) and cleft lip with or without cleft palate (CL/P). DESIGN: Five published case-control studies were included in the meta-analyis. Pooled Mantel-Haenszel odds ratios...

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Source

Identifiers

PMID: 15643916
DOI: 10.1597/02-128.1

Genes

TGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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