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Article

Variants of developmental genes (TGFA, TGFB3, and MSX1) and their associations with orofacial clefts: a case-parent triad analysis.

Genetic epidemiology - 1 Apr 2003

Jugessur Astanand, Lie Rolv T, Wilcox Allen J, Murray Jeffrey C, Taylor Jack A, Saugstad Ola D, Vindenes Hallvard A, Abyholm Frank

Abstract excerpt

We selected 262 case-parent triads from a population-based study of orofacial clefts in Norway, and examined variants of developmental genes TGFA, TGFB3, and MSX1 in the etiology of orofacial clefts. One hundred seventy-four triads of cleft lip cases (CL+/-P) and 88 triads of cleft palate only cases (CPO) were analyzed. There was little evidence for an association of any of these genes with CL+/-P. The strongest...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12652527
DOI: 10.1002/gepi.10223

Genes

TGFA
MSX1
CPO
TGFB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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