Article
[Gene-gene/gene-environment interaction of transforming growth factor-β signaling pathway and the risk of non-syndromic oral clefts].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Jun 2024
Hou Tianjiao, Zhou Zhibo, Wang Zhuqing, Wang Mengying, Wang Siyue, Peng Hexiang, Guo Huangda, Li Yixin, Zhang Hanyu, Qin Xueying, Wu Yiqun, Zheng Hongchen, Li Jing, Wu Tao, Zhu Hongping
Abstract excerpt
OBJECTIVE: To explore the association between polymorphisms of transforming growth factor-β (TGF-β) signaling pathway and non-syndromic cleft lip with or without cleft palate (NSCL/P) among Asian populations, while considering gene-gene interaction and gene-environment interaction. METHODS: A total of 1 038 Asian NSCL/P case-parent trios were ascertained from an international consortium, which conducted a...
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