Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oral clefts, transforming growth factor alpha gene variants, and maternal smoking: a population-based case-control study in Denmark, 1991-1994.

American journal of epidemiology - 1 Feb 1999

Christensen K, Olsen J, Nørgaard-Pedersen B, Basso O, Støvring H, Milhollin-Johnson L, Murray J C

Abstract excerpt

Studies in the United States have indicated that maternal first trimester smoking and infant transforming growth factor alpha (TGFA) locus mutations are associated with non-syndromic cleft lip and/or palate (CLP) and that a synergistic effect of these two risk factors occurs. Based on a Danish case-control study of CLP, the authors studied the effects of smoking and TGFA alleles in an ethnically homogeneous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cleft Palate

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Denmark

Share to Genotype

Share to Logistic Models

Share to Pregnancy

Share to Smoking

Share to Transforming Growth Factor alpha

Source

Identifiers

PMID: 9927220
DOI: 10.1093/oxfordjournals.aje.a009799

Genes

TGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oral clefts, transforming growth factor alpha gene variants, and maternal smoking: a population-based case-control study in Denmark, 1991-1994.PMID 9927220Read ↗

Orofacial clefts, parental cigarette smoking, and transforming growth factor-alpha gene variants.Semantic proximity Read ↗

Oral clefts, maternal smoking, and TGFA: a meta-analysis of gene-environment interaction.Semantic proximity Read ↗

Testing for interaction between maternal smoking and TGFA genotype among oral cleft cases born in Maryland 1992-1996.Semantic proximity Read ↗

Association between maternal exposure to tobacco, presence of TGFA gene, and the occurrence of oral clefts. A case control study.Semantic proximity Read ↗

Transforming Growth Factor Alpha Taq I Polymorphisms and Nonsyndromic Cleft Lip and/or Palate Risk: A Meta-Analysis.Semantic proximity Read ↗

Association between polymorphism of TGFA Taq I and cleft lip and/or palate: a meta-analysis.Semantic proximity Read ↗

Evaluation of Two Putative Susceptibility Loci for Oral Clefts in the Danish PopulationSemantic proximity Read ↗

Evidence that TGFA influences risk to cleft lip with/without cleft palate through unconventional genetic mechanisms.Semantic proximity Read ↗

Cleft palate, transforming growth factor alpha gene variants, and maternal exposures: assessing gene-environment interactions in case-parent triads.Semantic proximity Read ↗

Transforming growth factor alpha locus and nonsyndromic cleft lip with or without cleft palate: a reappraisal.Semantic proximity Read ↗

Genetic and environmental risk factors for submucous cleft palate.Semantic proximity Read ↗

Variants of developmental genes (TGFA, TGFB3, and MSX1) and their associations with orofacial clefts: a case-parent triad analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.