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Article

Infant TGF-alpha genotype, orofacial clefts, and maternal periconceptional multivitamin use.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jul 1998

Shaw G M, Wasserman C R, Murray J C, Lammer E J

Abstract excerpt

OBJECTIVE: We previously demonstrated a strong association between periconceptional maternal cigarette smoking, infant transforming growth factor-alpha (TGFa) genotype, and risk of orofacial clefts. Because serum folate may be decreased by cigarette smoking and because maternal periconceptional use of multivitamins containing folic acid has been associated with a reduced risk of clefting, we explored whether a...

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PMID: 9684776
DOI: 10.1597/1545-1569_1998_035_0366_itagoc_2.3.co_2

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