Article
Infant TGF-alpha genotype, orofacial clefts, and maternal periconceptional multivitamin use.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jul 1998
Shaw G M, Wasserman C R, Murray J C, Lammer E J
Abstract excerpt
OBJECTIVE: We previously demonstrated a strong association between periconceptional maternal cigarette smoking, infant transforming growth factor-alpha (TGFa) genotype, and risk of orofacial clefts. Because serum folate may be decreased by cigarette smoking and because maternal periconceptional u...
Topics
- Adult
- Case-Control Studies
- Cleft Lip
- Cleft Palate
- Cohort Studies
- Confidence Intervals
- DNA
- Female
- Folic Acid
- Genotype
- Heterozygote
- Homozygote
- Humans
- Infant, Newborn
- Interviews as Topic
- Male
- Odds Ratio
- Phenotype