Article
Candidate genes for nonsyndromic cleft lip and palate and maternal cigarette smoking and alcohol consumption: evaluation of genotype-environment interactions from a population-based case-control study of orofacial clefts.
Teratology - 1 Jan 1999
Romitti P A, Lidral A C, Munger R G, Daack-Hirsch S, Burns T L, Murray J C
Abstract excerpt
Previous studies suggest that the relationship between genes and nonsyndromic cleft lip +/- cleft palate (CLP) or cleft palate only (CP) may be modified by the environment. Using data from a population-based case-control study, we examined allelic variants for three genes, i.e., transforming growth factor alpha (TGFA), transforming growth factor beta 3 (TGFB3), and Msh (Drosophila) homeobox homolog 1 (MSX1), and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.