Article
Testing for interaction between maternal smoking and TGFA genotype among oral cleft cases born in Maryland 1992-1996.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Sept 1997
Beaty T H, Maestri N E, Hetmanski J B, Wyszynski D F, Vanderkolk C A, Simpson J C, McIntosh I, Smith E A, Zeiger J S, Raymond G V, Panny S R, Tifft C J, Lewanda A F, Cristion C A, Wulfsberg E A
Abstract excerpt
OBJECTIVE: Infants born in Maryland between June 1992 and June 1996 were used in a case-control study of nonsyndromic oral clefts to test for effects of maternal smoking and a polymorphic genetic marker at the transforming growth factor alpha (TGFA) locus, both of which have been reported to be risk factors for these common birth defects. DESIGN AND SETTING: Cases were infants with an oral cleft ascertained...
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