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Article

Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: a family-based genetic association study.

Breast cancer research : BCR - 1 Jan 2005

Ahsan Habibul, Whittemore Alice S, Chen Yu, Senie Ruby T, Hamilton Steven P, Wang Qiao, Gurvich Irina, Santella Regina M

Abstract excerpt

BACKGROUND: Case-control studies have reported inconsistent results concerning breast cancer risk and polymorphisms in genes that control endogenous estrogen biosynthesis. We report findings from the first family-based association study examining associations between female breast cancer risk and polymorphisms in two key estrogen-biosynthesis genes CYP17 (T-->C promoter polymorphism) and CYP19 (TTTA repeat...

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Identifiers

PMID: 15642171
DOI: 10.1186/bcr951
PMCID: PMC1064100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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