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Article

<i>CYP19</i> (aromatase) haplotypes and endometrial cancer risk

30 Mar 2005

Abstract excerpt

Endogenous estrogen exposure is an important determinant of endometrial cancer risk. Aromatase, encoded by CYP19, catalyzes the aromatization of androstenedione and testosterone to estrone and estradiol, respectively. Several common genetic polymorphisms in CYP19 have been identified, including a TCT insertion/deletion and a (TTTA)(n) repeat polymorphism in intron IV as well as a 3'UTR C/T polymorphism. We...

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Share to Endometrial and Cervical Cancer Treatments
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PMID: 15800924
DOI: 10.1002/ijc.21041

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