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Article

A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk.

International journal of cancer - 15 Jul 2000

Haiman C A, Hankinson S E, Spiegelman D, De Vivo I, Colditz G A, Willett W C, Speizer F E, Hunter D J

Abstract excerpt

The CYP19 gene codes for aromatase, a key steroidogenic enzyme involved in the conversion of androgens to estrogens. A tetranucleotide (TTTA) repeat polymorphism is present in intron 4 of CYP19; 2 out of 4 breast cancer case-control studies have reported a greater frequency of 2 specific alleles among affected women. We evaluated associations between CYP19 repeat alleles and breast cancer risk in a case-control...

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PMID: 10861475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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