Article
CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors.
Breast cancer research : BCR - 1 Jan 2003
Ambrosone Christine B, Moysich Kirsten B, Furberg Helena, Freudenheim Jo L, Bowman Elise D, Ahmed Sabrina, Graham Saxon, Vena John E, Shields Peter G
Abstract excerpt
BACKGROUND: Findings from previous studies regarding the association between the CYP17 genotype and breast cancer are inconsistent. We investigated the role of the MspAI genetic polymorphism in the 5' region of CYP17 on risk of breast cancer and as a modifier of reproductive risk factors. METHODS: Questionnaire and genotyping data were obtained from a population-based, case-control study of premenopausal (n =...
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