Article
Cellular factors required for protection from hyperoxia toxicity in Saccharomyces cerevisiae.
The Biochemical journal - 15 May 2005
Outten Caryn E, Falk Robert L, Culotta Valeria C
Abstract excerpt
Prolonged exposure to hyperoxia represents a serious danger to cells, yet little is known about the specific cellular factors that affect hyperoxia stress. By screening the yeast deletion library, we have identified genes that protect against high-O2 damage. Out of approx. 4800 mutants, 84 were identified as hyperoxia-sensitive, representing genes with diverse cellular functions, including transcription and...
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