Article
Mutants of Saccharomyces cerevisiae sensitive to oxidative and osmotic stress.
Current genetics - 1 Apr 1995
Krems B, Charizanis C, Entian K D
Abstract excerpt
Although oxidative stress is involved in many human diseases, little is known of its molecular basis in eukaryotes. In a genetic approach, S. cerevisiae was used to identify elements involved in oxidative stress. By using hydrogen peroxide as an agent for oxidative stress, 34 mutants were identified. All mutants were recessive and fell into 16 complementation groups (pos1 to pos16 for peroxide sensitivity). They...
Topics
- Cell Division
- Genes, Fungal
- Hydrogen Peroxide
- Mutagenesis
- Mutation
- Osmotic Pressure
- Oxidative Stress
- Saccharomyces cerevisiae