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Article

Large-scale investigation of oxygen response mutants in <i>Saccharomyces cerevisiae</i>

22 Feb 2013

Abstract excerpt

A genome-wide screen of a yeast non-essential gene-deletion library was used to identify sick phenotypes due to oxygen deprivation. The screen provided a manageable list of 384 potentially novel as well as known oxygen responding (anoxia-survival) genes. The gene-deletion mutants were further assayed for sensitivity to ferrozine and cobalt to obtain a subset of 34 oxygen-responsive candidate genes including the...

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PMID: 23467670
DOI: 10.1039/c3mb25516f

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