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Article

Universal and radiation-specific loci influence murine susceptibility to radiation-induced pulmonary fibrosis.

Cancer research - 1 Jul 2002

Haston Christina K, Zhou Xinhui, Gumbiner-Russo Laura, Irani Roxanna, Dejournett Robert, Gu Xiangjun, Weil Michael, Amos Christopher I, Travis Elizabeth L

Abstract excerpt

Susceptibility to radiation-induced pulmonary fibrosis is a heritable trait in mice. In a prior study of C57BL/6J (susceptible), C3Hf/Kam (resistant), and F1 and F2 mice derived from these strains, we estimated that approximately 38% of the measured phenotypic variation could be attributed to effects from a few genetic factors. In addition, we identified one genetic factor on chromosome 17 in the MHC region. To...

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PMID: 12097289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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