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Article

Unfavourable prognosis associated with K-ras gene mutation in pancreatic cancer surgical margins.

Gut - 1 Nov 2006

Kim J, Reber H A, Dry S M, Elashoff D, Chen S L, Umetani N, Kitago M, Hines O J, Kazanjian K K, Hiramatsu S, Bilchik A J, Yong S, Shoup M, Hoon D S B

Abstract excerpt

BACKGROUND: Despite intent to cure surgery with negative resection margins, locoregional recurrence is common in pancreatic cancer. AIMS: To determine whether detection of K-ras gene mutation in the histologically negative surgical margins of pancreatic cancer reflects unrecognised disease. PATIENTS: Seventy patients who underwent curative resection for pancreatic ductal adenocarcinoma were evaluated. METHODS:...

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Identifiers

PMID: 16682430
DOI: 10.1136/gut.2005.083063
PMCID: PMC1860104

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Source receipt: pubmed, retrieved 7 Sept 2026.

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