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Article

K-ras mutations in colorectal adenocarcinomas and neighbouring transitional mucosa.

European journal of cancer (Oxford, England : 1990) - 1 Dec 1998

Zhang H, Nordenskjöld B, Dufmats M, Söderkvist P, Sun X F

Abstract excerpt

The K-ras gene in codons 12 and 13 was investigated using allele-specific polymerase chain reaction in matched normal mucosa (n = 106), transitional mucosa (n = 69) and tumours (n = 149) from 149 patients with colorectal adenocarcinomas. K-ras mutations in codon 12 were detected in 41/149 (28%) of tumours and 4/69 (6%) of transitional mucosa samples, but not in the normal mucosa. Further, mutation rates were...

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Identifiers

PMID: 10070310
DOI: 10.1016/s0959-8049(98)00283-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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