Article
Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner.
Traffic (Copenhagen, Denmark) - 1 Feb 2005
Savina Ariel, Fader Claudio M, Damiani María T, Colombo María Isabel
Abstract excerpt
Multivesicular bodies (MVBs) are membranous structures within 60-100 nm diameter vesicles accumulate. MVBs are generated after invagination and pinching off of the endosomal membrane in the lumen of the vacuole. In certain cell types, fusion of MVBs with the plasma membrane results in the release of the internal vesicles called exosomes. In this report we have examined how an increase in cytosolic calcium affects...
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