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Article

Characterization of Rab5:Q79L-stimulated endosome fusion.

Archives of biochemistry and biophysics - 1 Feb 1996

Barbieri M A, Li G, Mayorga L S, Stahl P D

Abstract excerpt

Fusion of intracellular membrane-bound compartments is a common step in the transport of macromolecules along the endocytic and secretory pathways. Previous work has shown that GTP gamma S stimulates endosome fusion in the presence of low concentrations of cytosol. In this study, we have characterized the effect of rab5:Q79L, a mutant with reduced GTPase activity, on endosome fusion in a cell-free assay....

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Identifiers

PMID: 8579373
DOI: 10.1006/abbi.1996.0047

Genes

NSF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of Rab5:Q79L-stimulated endosome fusion.PMID 8579373Read ↗

Evidence for a symmetrical requirement for Rab5-GTP in in vitro endosome-endosome fusion.Semantic proximity Read ↗

Receptor and membrane recycling can occur with unaltered efficiency despite dramatic Rab5(q79l)-induced changes in endosome geometry.Semantic proximity Read ↗

Inhibition of endosome fusion by wortmannin persists in the presence of activated Rab5.Semantic proximity Read ↗

Sequential roles for phosphatidylinositol 3-phosphate and Rab5 in tethering and fusion of early endosomes via their interaction with EEA1.Semantic proximity Read ↗

Remodeling of endosomes during lysosome biogenesis involves 'kiss and run' fusion events regulated by rab5.Semantic proximity Read ↗

SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions.Semantic proximity Read ↗

Live Salmonella recruits N-ethylmaleimide-sensitive fusion protein on phagosomal membrane and promotes fusion with early endosome.Semantic proximity Read ↗

Expression and properties of Rab7 in endosome function.Semantic proximity Read ↗

Effect of EGF-receptor tyrosine kinase inhibitor on Rab5 function during endocytosis.Semantic proximity Read ↗

Exocytosis of post-Golgi vesicles is regulated by components of the endocytic machinery.Semantic proximity Read ↗

Fusion of cells by flipped SNAREs.Semantic proximity Read ↗

Dimerization of small GTPase Rab5.Semantic proximity Read ↗

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