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Article

Annexin2 coating the surface of enlargeosomes is needed for their regulated exocytosis.

The EMBO journal - 29 Nov 2006

Lorusso Anna, Covino Cesare, Priori Giuseppina, Bachi Angela, Meldolesi Jacopo, Chieregatti Evelina

Abstract excerpt

Enlargeosomes are small cytoplasmic vesicles that undergo rapid, Ca2+-dependent exo/endocytosis. The role of the cytoskeleton in these processes was unknown. In PC12-27 cells, microtubule disassembly had little effect on enlargeosomes, whereas microfilament disassembly increased markedly both their resting and stimulated exocytosis, and inhibited their endocytosis. Even at rest enlargeosomes are coated at their...

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Share to Actin Cytoskeleton
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17082761
DOI: 10.1038/sj.emboj.7601419
PMCID: PMC1679766

Genes

NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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