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Article

Requirement for annexin A1 in plasma membrane repair.

The Journal of biological chemistry - 17 Nov 2006

McNeil Anna K, Rescher Ursula, Gerke Volker, McNeil Paul L

Abstract excerpt

Ca2+ entering a cell through a torn or disrupted plasma membrane rapidly triggers a combination of homotypic and exocytotic membrane fusion events. These events serve to erect a reparative membrane patch and then anneal it to the defect site. Annexin A1 is a cytosolic protein that, when activated by micromolar Ca2+, binds to membrane phospholipids, promoting membrane aggregation and fusion. We demonstrate here...

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Identifiers

PMID: 16984915
DOI: 10.1074/jbc.M606406200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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