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Article

Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts.

AIDS (London, England) - 3 Jan 2005

Martin Annalise M, Nolan David, James Ian, Cameron Paul, Keller Jean, Moore Corey, Phillips Elizabeth, Christiansen Frank T, Mallal Simon

Abstract excerpt

Genetic (human leukocyte antigen), disease-related and demographic risk factors for nevirapine reactions were examined in a nevirapine-exposed cohort. Cases involving combinations of hepatitis, fever or rash were associated with an interaction between HLA-DRB1*0101 and the percentage of CD4, whereas no associations were detected for isolated rash. These data suggest that HLA-DRB1*0101 and the CD4 status may...

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Identifiers

PMID: 15627041
DOI: 10.1097/00002030-200501030-00014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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