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Article

Association between CYP2B6 polymorphisms and Nevirapine-induced SJS/TEN: a pharmacogenetics study.

European journal of clinical pharmacology - 1 Nov 2013

Ciccacci Cinzia, Di Fusco Davide, Marazzi Maria C, Zimba Ines, Erba Fulvio, Novelli Giuseppe, Palombi Leonardo, Borgiani Paola, Liotta Giuseppe

Abstract excerpt

PURPOSE: Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor, widely prescribed for type 1 human immunodeficiency virus infection. A small proportion of individuals treated with NVP experience severe cutaneous adverse events, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Our aim was to verify whether genetic variability in NVP-metabolizing cytochromes or in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23774940
DOI: 10.1007/s00228-013-1549-x

Genes

ABCB1
ABCC10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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