Article
HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients.
Pharmacogenetics and genomics - 1 Feb 2009
Chantarangsu Soranun, Mushiroda Taisei, Mahasirimongkol Surakameth, Kiertiburanakul Sasisopin, Sungkanuparph Somnuek, Manosuthi Weerawat, Tantisiriwat Woraphot, Charoenyingwattana Angkana, Sura Thanyachai, Chantratita Wasun, Nakamura Yusuke
Abstract excerpt
OBJECTIVE: Investigation of a possible involvement of differences in human leukocyte antigens (HLA) in the risk of nevirapine (NVP)-induced skin rash among HIV-infected patients. METHODS: A step-wise case-control association study was conducted. The first set of samples consisted of 80 samples fr...
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