Article
HLA-dependent hypersensitivity reaction to nevirapine in Chinese Han HIV-infected patients.
AIDS research and human retroviruses - 1 Jun 2012
Gao Shicheng, Gui Xi-En, Liang Ke, Liu Zhang, Hu Jinzhi, Dong Bo
Abstract excerpt
In this study, one hundred and three HIV-positive Chinese Han patients treated with a nevirapine (NVP)-based regimens were investigated for the association between nevirapine hypersensitivity reaction (NVP HSR) and human leukocyte antigen (HLA) allele. HLA-Cw, -DRB1 alleles were determined in 32 NVP HSR cases and 71 NVP-tolerant patients. We found that considerable overlap was observed for the clinical and...
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