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HLA-DRB1 * 01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz

19 Feb 2008

Abstract excerpt

HLA typing, demographic and immunological risk factors for nevirapine and efavirenz reactions were studied in a French cohort of HIV patients. Cases with isolated rash were significantly associated with HLA-DRB101 allele. No liver toxicity was observed and no association was detected with the percentage of CD4 T-cells. This study suggests that HLA-DRB101 allele plays an important role in susceptibility to...

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PMID: 18301070
DOI: 10.1097/qad.0b013e3282f37812

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