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Eight Novel Single Nucleotide Polymorphisms in ABCG2/BCRP in Japanese Cancer Patients Administered Irinotacan

1 Jan 2003

Abstract excerpt

Eight novel single nucleotide polymorphisms (SNPs) were found in the gene encoding the ATP-binding cassette transporter, ABCG2/BCRP, from 60 Japanese individuals administered the anti-cancer drug irinotecan. The detected SNPs were as follows: 1) SNP, MPJ6_AG2005 (IVS2-93T>C); Gene Name, ABCG2; Accession Number, NT_006204; 2) SNP, MPJ6_AG2007 (IVS3+71_72 insT); Gene Name, ABCG2; Accession Number, NT_006204; 3)...

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Identifiers

PMID: 15618737
DOI: 10.2133/dmpk.18.212

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