Article
[Advance of research on relationship between ABCG2 and drug resistance in hematologic malignancies - review].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2009
Qu Shi-Qiang, Fu Zheng-Zheng, Wu De-Pei
Abstract excerpt
ABCG2, a half-transporter concerning with the endo and exon-toxin-efflux, plays an important role in protecting the normal tissues from the toxin-hurt as well as mediating the multidrug resistance, because many of the chemotherapeutic drugs are the substrate of ABCG2. In this paper, the advance of research about this gene's single nucleotide polymorphisms (SNPs) was explained concisely. The relationship among...
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