Article
[Correlation of MDR1 and ABCG2 genetic polymorphisms with the efficacy and adverse events of irinotecan chemotherapy in patients with colorectal cancer].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 1 Jun 2013
Sun Zhi-wei, Wang Xi-cheng, Gao Jing, Li Jie, Li Yan-yan, Dang Yun-zhi, Shen Lin
Abstract excerpt
OBJECTIVE: To investigate the correlation of MDR1 and ABCG2 genetic polymorphisms with the efficacy and adverse events of irinotecan chemotherapy in patients with colorectal cancer (CRC). METHODS: Clinical data of CRC patients treated with irinotecan-based chemotherapy in the Peking University Cancer Hospital between January 1996 and December 2011 were collected, and their blood samples were collected...
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