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Article

Pharmacodynamic modeling of ciprofloxacin resistance in Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Jan 2005

Campion Jeffrey J, McNamara Patrick J, Evans Martin E

Abstract excerpt

Three pharmacodynamic models of increasing complexity, designed for two subpopulations of bacteria with different susceptibilities, were developed to describe and predict the evolution of resistance to ciprofloxacin in Staphylococcus aureus by using pharmacokinetic, viable count, subpopulation, and resistance mechanism data obtained from in vitro system experiments. A two-population model with unique growth and...

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Identifiers

PMID: 15616298
DOI: 10.1128/AAC.49.1.209-219.2005
PMCID: PMC538881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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