Article
Evolution of Ciprofloxacin-Resistant <i>Staphylococcus aureus</i> in In Vitro Pharmacokinetic Environments
24 Nov 2004
Abstract excerpt
The development of novel antibacterial agents is decreasing despite increasing resistance to presently available agents among common pathogens. Insights into relationships between pharmacodynamics and resistance may provide ways to optimize the use of existing agents. The evolution of resistance was examined in two ciprofloxacin-susceptible Staphylococcus aureus strains exposed to in vitro-simulated clinical and...
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