Article
Nte1p-mediated deacylation of phosphatidylcholine functionally interacts with Sec14p.
The Journal of biological chemistry - 4 Mar 2005
Murray J Pedro Fernández, McMaster Christopher R
Abstract excerpt
Deciphering the function of the essential yeast Sec14p protein has revealed a regulatory interface between cargo secretion from Golgi and lipid homeostasis. Abrogation of the CDP-choline (CDP-Cho) pathway for phosphatidylcholine (PC) synthesis allows for life in the absence of the otherwise essential Sec14p. Nte1p, the product of open reading frame YML059c, is an integral membrane phospholipase against...
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