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Article

Neuropathy target esterase and phospholipid deacylation.

Biochimica et biophysica acta - 15 Sept 2005

Glynn Paul

Abstract excerpt

Certain organophosphates react with the active site serine residue of neuropathy target esterase (NTE) and cause axonal degeneration and paralysis. Cloning of NTE revealed the presence of homologues in eukaryotes from yeast to man and that the protein has both a catalytic and a regulatory domain. The latter contains sequences similar to the regulatory subunit of protein kinase A, suggesting that NTE may bind...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16137924
DOI: 10.1016/j.bbalip.2005.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Neuropathy target esterase and phospholipid deacylation.PMID 16137924Read ↗

Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells.Semantic proximity Read ↗

Neuropathy target esterase (NTE): overview and future.Semantic proximity Read ↗

Neuropathy target esterase and a homologous Drosophila neurodegeneration-associated mutant protein contain a novel domain conserved from bacteria to man.Semantic proximity Read ↗

Neuropathy Target Esterase Is Required for Adult Vertebrate Axon MaintenanceSemantic proximity Read ↗

Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity.Semantic proximity Read ↗

Glycerophosphocholine catabolism as a new route for choline formation for phosphatidylcholine synthesis by the Kennedy pathway.Semantic proximity Read ↗

Neuropathy target esterase: An essential enzyme for neural development and axonal maintenanceSemantic proximity Read ↗

Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila.Semantic proximity Read ↗

Neuropathy target esterase gene mutations cause motor neuron disease.Semantic proximity Read ↗

The cyclic nucleotide binding sites of Swiss-Cheese, the <i>Drosophila</i> orthologue of human PNPLA6, are required for its catalytic functionSemantic proximity Read ↗

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The emerging physiological roles of the glycerophosphodiesterase familySemantic proximity Read ↗

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