Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover.

European journal of biochemistry - 1 Aug 2003

Schnabl Martina, Oskolkova Olga V, Holic Roman, Brezná Barbara, Pichler Harald, Zágorsek Milos, Kohlwein Sepp D, Paltauf Fritz, Daum Günther, Griac Peter

Abstract excerpt

Sec14p of the yeast Saccharomyces cerevisiae is involved in protein secretion and regulation of lipid synthesis and turnover in vivo, but acts as a phosphatidylinositol-phosphatidylcholine transfer protein in vitro. In this work, the five homologues of Sec14p, Sfh1p-Sfh5p, were subjected to biochemical and cell biological analysis to get a better view of their physiological role. We show that overexpression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungal Proteins
Share to Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Fluorescence

Share to Phosphatidylcholines

Share to Phospholipase D

Share to Phospholipid Transfer Proteins

Share to Phospholipids

Share to Saccharomyces cerevisiae Proteins

Source

Identifiers

PMID: 12869188
DOI: 10.1046/j.1432-1033.2003.03688.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover.PMID 12869188Read ↗

Nte1p-mediated deacylation of phosphatidylcholine functionally interacts with Sec14p.Semantic proximity Read ↗

Osh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature.Semantic proximity Read ↗

A phosphatidylinositol-transfer protein and phosphatidylinositol-4-phosphate 5-kinase control Cdc42 to regulate the actin cytoskeleton and secretory pathway in yeast.Semantic proximity Read ↗

Global analysis of protein palmitoylation in yeast.Semantic proximity Read ↗

The sterol-binding protein Kes1/Osh4p is a regulator of polarized exocytosis.Semantic proximity Read ↗

Regulation of phospholipid biosynthesis by phosphatidylinositol transfer protein Sec14p and its homologues. A critical role for phosphatidic acid.Semantic proximity Read ↗

A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae.Semantic proximity Read ↗

SFH2 regulates fatty acid synthase activity in the yeast Saccharomyces cerevisiae and is critical to prevent saturated fatty acid accumulation in response to haem and oleic acid depletion.Semantic proximity Read ↗

Genetic manipulation of palmitoylethanolamide production and inactivation in Saccharomyces cerevisiae.Semantic proximity Read ↗

An essential role for a phospholipid transfer protein in yeast Golgi function.Semantic proximity Read ↗

Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae.Semantic proximity Read ↗

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.