The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity.

doi:10.1073/pnas.92.1.112

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Article

The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity.

Proceedings of the National Academy of Sciences of the United States of America - 3 Jan 1995

Skinner H B, McGee T P, McMaster C R, Fry M R, Bell R M, Bankaitis V A

Abstract excerpt

The Saccharomyces cerevisiae protein SEC14p is required for Golgi function and cell viability in vivo. This requirement is obviated by mutations that specifically inactivate the CDP-choline pathway for phosphatidylcholine biosynthesis. The biochemical basis for the in vivo relationship between SE...

Topics

Carbon Radioisotopes
Carrier Proteins
Choline
Choline-Phosphate Cytidylyltransferase
Cloning, Molecular
Cytidine Diphosphate Choline
Cytosol
Escherichia coli
Genotype
Golgi Apparatus
Intracellular Membranes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kinetics

Ligands

Membrane Proteins

Models, Biological

Nucleotidyltransferases

Phosphatidylinositols

Phospholipid Transfer Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 7816798
DOI: 10.1073/pnas.92.1.112
PMCID: PMC42827

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7816798-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity.PMID 7816798Read ↗

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