Article
The sterol-binding protein Kes1/Osh4p is a regulator of polarized exocytosis.
Traffic (Copenhagen, Denmark) - 1 Nov 2011
Alfaro Gabriel, Johansen Jesper, Dighe Shubha A, Duamel Giselle, Kozminski Keith G, Beh Christopher T
Abstract excerpt
Oxysterol-binding protein (OSBP)-related protein Kes1/ Osh4p is implicated in nonvesicular sterol transfer between membranes in Saccharomyces cerevisiae. However, we found that Osh4p associated with exocytic vesicles that move from the mother cell into the bud, where Osh4p facilitated vesicle docking by the exocyst tethering complex at sites of polarized growth on the plasma membrane. Osh4p formed complexes with...
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