Article
Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release.
Diabetic medicine : a journal of the British Diabetic Association - 1 Jan 2005
Hamid Y H, Vissing H, Holst B, Urhammer S A, Pyke C, Hansen S K, Glümer C, Borch-Johnsen K, Jørgensen T, Schwartz T W, Pedersen O, Hansen T
Abstract excerpt
AIMS: Recently, a novel human G protein-coupled receptor 40 (GPR40), which is predominantly expressed in pancreatic islets, was shown to mediate an amplifying effect of long-chain fatty acids on glucose-induced insulin secretion. The present aim was to examine the coding region of GPR40 for variation and to assess whether identified variants confer an increased risk of Type 2 diabetes or altered insulin release....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.