Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells.

doi:10.1007/s001250051051

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Article

Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells.

Diabetologia - 1 Oct 1998

Almind K, Ambye L, Urhammer S A, Hansen T, Echwald S M, Holst J J, Gromada J, Thorens B, Pedersen O

Abstract excerpt

The two incretins, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), are insulinotropic factors released from the small intestine to the blood stream in response to oral glucose ingestion. The insulinotropic effect of GLP-1 is maintained in patients with Type...

Topics

Alleles
Animals
C-Peptide
Cell Line
Cricetinae
Cricetulus
Cyclic AMP
DNA Mutational Analysis
Diabetes Mellitus, Type 2
Gastric Inhibitory Polypeptide
Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Frequency

Glucose Tolerance Test

Homozygote

Humans

Islets of Langerhans

Mutation

Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 9794107
DOI: 10.1007/s001250051051

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9794107-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells.PMID 9794107Read ↗

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