Article
Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups.
BMC medical genetics - 2 Mar 2009
Vogel Carla I G, Scherag André, Brönner Günter, Nguyen Thuy T, Wang Hai-Jun, Grallert Harald, Bornhorst Alexa, Rosskopf Dieter, Völzke Henry, Reinehr Thomas, Rief Winfried, Illig Thomas, Wichmann H-Erich, Schäfer Helmut, Hebebrand Johannes, Hinney Anke
Abstract excerpt
BACKGROUND: Gastric inhibitory polypeptide (GIP) is postulated to be involved in type 2 diabetes mellitus and obesity. It exerts its function through its receptor, GIPR. We genotyped three GIPR SNPs (rs8111428, rs2302382 and rs1800437) in German families with at least one obese index patient, two case-control studies and two cross-sectional population-based studies. METHODS: Genotyping was performed by MALDI-TOF,...
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